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The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro
BACKGROUND: There is no established biochemical basis for the neurotoxicity of mefloquine. We investigated the possibility that the acute in vitro neurotoxicity of mefloquine might be mediated through a disruptive effect of the drug on endoplasmic reticulum (ER) calcium homeostasis. METHODS: Laser s...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC194860/ https://www.ncbi.nlm.nih.gov/pubmed/12848898 http://dx.doi.org/10.1186/1475-2875-2-14 |