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The anti-apoptotic factor Che-1/AATF links transcriptional regulation, cell cycle control, and DNA damage response

Che-1 is a RNA polymerase II binding protein involved in the transcriptional regulation of E2F target genes and in cell proliferation. Recently, it has been shown that Che-1 accumulates in cells responding to genotoxic agents such as Doxorubicin and ionizing radiation. The DNA damage-activated check...

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Detalles Bibliográficos
Autores principales: Passananti, Claudio, Fanciulli, Maurizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1948887/
https://www.ncbi.nlm.nih.gov/pubmed/17634135
http://dx.doi.org/10.1186/1747-1028-2-21