Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate

The anti-malarial artesunate also exerts profound anti-cancer activity. The susceptibility of tumor cells to artesunate can be enhanced by ferrous iron. The transferrin receptor (TfR) is involved in iron uptake by internalization of transferrin and is over-expressed in rapidly growing tumors. The AT...

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Detalles Bibliográficos
Autores principales: Kelter, Gerhard, Steinbach, Daniel, Konkimalla, Venkata Badireenath, Tahara, Tsuyoshi, Taketani, Shigeru, Fiebig, Heinz-Herbert, Efferth, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949049/
https://www.ncbi.nlm.nih.gov/pubmed/17726528
http://dx.doi.org/10.1371/journal.pone.0000798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949049/
https://www.ncbi.nlm.nih.gov/pubmed/17726528
http://dx.doi.org/10.1371/journal.pone.0000798

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