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Quadrupling Muscle Mass in Mice by Targeting TGF-ß Signaling Pathways
Myostatin is a transforming growth factor-ß family member that normally acts to limit skeletal muscle growth. Mice genetically engineered to lack myostatin activity have about twice the amount of muscle mass throughout the body, and similar effects are seen in cattle, sheep, dogs, and a human with n...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949143/ https://www.ncbi.nlm.nih.gov/pubmed/17726519 http://dx.doi.org/10.1371/journal.pone.0000789 |