GAD1 mRNA Expression and DNA Methylation in Prefrontal Cortex of Subjects with Schizophrenia

Dysfunction of prefrontal cortex in schizophrenia includes changes in GABAergic mRNAs, including decreased expression of GAD1, encoding the 67 kDa glutamate decarboxylase (GAD(67)) GABA synthesis enzyme. The underlying molecular mechanisms remain unclear. Alterations in DNA methylation as an epigene...

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Detalles Bibliográficos
Autores principales: Huang, Hsien-Sung, Akbarian, Schahram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950080/
https://www.ncbi.nlm.nih.gov/pubmed/17726539
http://dx.doi.org/10.1371/journal.pone.0000809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950080/
https://www.ncbi.nlm.nih.gov/pubmed/17726539
http://dx.doi.org/10.1371/journal.pone.0000809

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