Toll-Like Receptor 2 Impairs Host Defense in Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis)

BACKGROUND: Toll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the most important receptor for gram-positive bacteria, while TLR4 is regarded as the gram-negative TLR. Melioidosis...

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Detalles Bibliográficos
Autores principales: Wiersinga, W. Joost, Wieland, Catharina W, Dessing, Mark C, Chantratita, Narisara, Cheng, Allen C, Limmathurotsakul, Direk, Chierakul, Wirongrong, Leendertse, Masja, Florquin, Sandrine, de Vos, Alex F, White, Nicholas, Dondorp, Arjen M, Day, Nicholas P, Peacock, Sharon J, van der Poll, Tom
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950213/
https://www.ncbi.nlm.nih.gov/pubmed/17676990
http://dx.doi.org/10.1371/journal.pmed.0040248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950213/
https://www.ncbi.nlm.nih.gov/pubmed/17676990
http://dx.doi.org/10.1371/journal.pmed.0040248

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