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Beta-Catenin Signaling Plays a Disparate Role in Different Phases of Fracture Repair: Implications for Therapy to Improve Bone Healing

BACKGROUND: Delayed fracture healing causes substantial disability and usually requires additional surgical treatments. Pharmacologic management to improve fracture repair would substantially improve patient outcome. The signaling pathways regulating bone healing are beginning to be unraveled, and t...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Whetstone, Heather C, Lin, Alvin C, Nadesan, Puviindran, Wei, Qingxia, Poon, Raymond, Alman, Benjamin A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950214/
https://www.ncbi.nlm.nih.gov/pubmed/17676991
http://dx.doi.org/10.1371/journal.pmed.0040249