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The Polyol Pathway as a Mechanism for Diabetic Retinopathy: Attractive, Elusive, and Resilient
The polyol pathway is a two-step metabolic pathway in which glucose is reduced to sorbitol, which is then converted to fructose. It is one of the most attractive candidate mechanisms to explain, at least in part, the cellular toxicity of diabetic hyperglycemia because (i) it becomes active when intr...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950230/ https://www.ncbi.nlm.nih.gov/pubmed/18224243 http://dx.doi.org/10.1155/2007/61038 |