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Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant

BACKGROUND: Plasmodium falciparum is the predominant human malaria species in Mozambique and a lead cause of mortality among children and pregnant women nationwide. Sulphadoxine/pyrimethamine (S/P) is used as first line antimalarial treatment as a partner drug in combination with artesunate. METHODS...

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Detalles Bibliográficos
Autores principales: Fernandes, Natércia, Figueiredo, Paula, do Rosário, Virgilio E, Cravo, Pedro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950477/
https://www.ncbi.nlm.nih.gov/pubmed/17378942
http://dx.doi.org/10.1186/1475-2875-6-35