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Experiments Suggest that Simulations May Overestimate Electrostatic Contributions to the Mechanical Stability of a Fibronectin Type III Domain

Steered molecular dynamics simulations have previously been used to investigate the mechanical properties of the extracellular matrix protein fibronectin. The simulations suggest that the mechanical stability of the tenth type III domain from fibronectin (FNfn10) is largely determined by a number of...

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Detalles Bibliográficos
Autores principales: Ng, Sean P., Clarke, Jane
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950483/
https://www.ncbi.nlm.nih.gov/pubmed/17594907
http://dx.doi.org/10.1016/j.jmb.2007.06.015