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Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging

BACKGROUND: Cell division occurs during normal human development and aging. Despite the likely importance of cell division to human pathology, it has been difficult to infer somatic cell mitotic ages (total numbers of divisions since the zygote) because direct counting of lifetime numbers of divisio...

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Detalles Bibliográficos
Autores principales: Chu, Michelle W, Siegmund, Kimberly D, Eckstam, Carrie L, Kim, Jung Yeon, Yang, Allen S, Kanel, Gary C, Tavaré, Simon, Shibata, Darryl
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950491/
https://www.ncbi.nlm.nih.gov/pubmed/17672908
http://dx.doi.org/10.1186/1471-2350-8-50