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A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose

PURPOSE: Current methods for quantifying effects of DNA repair modifiers on radiation sensitivity assume a constant effect independent of the radiation dose received. The aim of this study was to develop and evaluate a modelling strategy by which radiation dose dependent effects of DNA repair inhibi...

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Detalles Bibliográficos
Autores principales: Chalmers, Anthony J, Bentzen, Soeren M, Buffa, Francesca M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950494/
https://www.ncbi.nlm.nih.gov/pubmed/17640390
http://dx.doi.org/10.1186/1742-4682-4-25