Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism

The mechanisms of processivity factors of herpesvirus DNA polymerases remain poorly understood. The proposed processivity factor for human cytomegalovirus DNA polymerase is a DNA-binding protein, UL44. Previous findings, including the crystal structure of UL44, have led to the hypothesis that UL44 b...

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Detalles Bibliográficos
Autores principales: Loregian, Arianna, Sinigalia, Elisa, Mercorelli, Beatrice, Palù, Giorgio, Coen, Donald M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950537/
https://www.ncbi.nlm.nih.gov/pubmed/17617644
http://dx.doi.org/10.1093/nar/gkm506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950537/
https://www.ncbi.nlm.nih.gov/pubmed/17617644
http://dx.doi.org/10.1093/nar/gkm506

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