Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease

The human LINE-1 endonuclease (L1-EN) is the targeting endonuclease encoded by the human LINE-1 (L1) retrotransposon. L1-EN guides the genomic integration of new L1 and Alu elements that presently account for ∼28% of the human genome. L1-EN bears considerable technological interest, because its targ...

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Detalles Bibliográficos
Autores principales: Repanas, Kostas, Zingler, Nora, Layer, Liliana E., Schumann, Gerald G., Perrakis, Anastassis, Weichenrieder, Oliver
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950540/
https://www.ncbi.nlm.nih.gov/pubmed/17626046
http://dx.doi.org/10.1093/nar/gkm516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950540/
https://www.ncbi.nlm.nih.gov/pubmed/17626046
http://dx.doi.org/10.1093/nar/gkm516

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