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A Genetic Basis of Susceptibility to Acute Pyelonephritis

BACKGROUND: For unknown reasons, urinary tract infections (UTIs) are clustered in certain individuals. Here we propose a novel, genetically determined cause of susceptibility to acute pyelonephritis, which is the most severe form of UTI. The IL-8 receptor, CXCR1, was identified as a candidate gene w...

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Detalles Bibliográficos
Autores principales: Lundstedt, Ann-Charlotte, McCarthy, Shane, Gustafsson, Mattias C.U., Godaly, Gabriela, Jodal, Ulf, Karpman, Diana, Leijonhufvud, Irene, Lindén, Carin, Martinell, Jeanette, Ragnarsdottir, Bryndis, Samuelsson, Martin, Truedsson, Lennart, Andersson, Björn, Svanborg, Catharina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950574/
https://www.ncbi.nlm.nih.gov/pubmed/17786197
http://dx.doi.org/10.1371/journal.pone.0000825