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The Chop Gene Contains an Element for the Positive Regulation of the Mitochondrial Unfolded Protein Response

We have previously reported on the discovery of a mitochondrial specific unfolded protein response (mtUPR) in mammalian cells, in which the accumulation of unfolded protein within the mitochondrial matrix results in the transcriptional activation of nuclear genes encoding mitochondrial stress protei...

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Detalles Bibliográficos
Autores principales: Horibe, Tomohisa, Hoogenraad, Nicholas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950685/
https://www.ncbi.nlm.nih.gov/pubmed/17848986
http://dx.doi.org/10.1371/journal.pone.0000835