GSK-3β Controls Osteogenesis through Regulating Runx2 Activity

Despite accumulated knowledge of various signalings regulating bone formation, the molecular network has not been clarified sufficiently to lead to clinical application. Here we show that heterozygous glycogen synthase kinase-3β (GSK-3β)-deficient mice displayed an increased bone formation due to an...

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Detalles Bibliográficos
Autores principales: Kugimiya, Fumitaka, Kawaguchi, Hiroshi, Ohba, Shinsuke, Kawamura, Naohiro, Hirata, Makoto, Chikuda, Hirotaka, Azuma, Yoshiaki, Woodgett, James R., Nakamura, Kozo, Chung, Ung-il
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950686/
https://www.ncbi.nlm.nih.gov/pubmed/17786208
http://dx.doi.org/10.1371/journal.pone.0000837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950686/
https://www.ncbi.nlm.nih.gov/pubmed/17786208
http://dx.doi.org/10.1371/journal.pone.0000837

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