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Sp1 Expression Is Disrupted in Schizophrenia; A Possible Mechanism for the Abnormal Expression of Mitochondrial Complex I Genes, NDUFV1 and NDUFV2

BACKGROUND: The prevailing hypothesis regards schizophrenia as a polygenic disease, in which multiple genes combine with each other and with environmental stimuli to produce the variance of its clinical symptoms. We investigated whether the ubiquitous transcription factor Sp1 is abnormally expressed...

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Detalles Bibliográficos
Autores principales: Ben-Shachar, Dorit, Karry, Rachel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950689/
https://www.ncbi.nlm.nih.gov/pubmed/17786189
http://dx.doi.org/10.1371/journal.pone.0000817