HIF2α reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma

BACKGROUND: HIF2α/EPAS1 is a hypoxia-inducible transcription factor involved in catecholamine homeostasis, vascular remodelling, physiological angiogenesis and adipogenesis. It is overexpressed in many cancerous tissues, but its exact role in tumour progression remains to be clarified. METHODS: In o...

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Detalles Bibliográficos
Autores principales: Favier, Judith, Lapointe, Stéphanie, Maliba, Ricardo, Sirois, Martin G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950713/
https://www.ncbi.nlm.nih.gov/pubmed/17655754
http://dx.doi.org/10.1186/1471-2407-7-139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950713/
https://www.ncbi.nlm.nih.gov/pubmed/17655754
http://dx.doi.org/10.1186/1471-2407-7-139

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