Cargando…

HIF2α reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma

BACKGROUND: HIF2α/EPAS1 is a hypoxia-inducible transcription factor involved in catecholamine homeostasis, vascular remodelling, physiological angiogenesis and adipogenesis. It is overexpressed in many cancerous tissues, but its exact role in tumour progression remains to be clarified. METHODS: In o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Favier, Judith, Lapointe, Stéphanie, Maliba, Ricardo, Sirois, Martin G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950713/ https://www.ncbi.nlm.nih.gov/pubmed/17655754 http://dx.doi.org/10.1186/1471-2407-7-139

Ejemplares similares

HIF-1α and HIF-2α induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide
por: Feng, Nan, et al.
Publicado: (2016)

HIF-1α and HIF-2α: Siblings in Promoting Angiogenesis of Residual Hepatocellular Carcinoma after High-Intensity Focused Ultrasound Ablation
por: Wu, Lun, et al.
Publicado: (2014)

The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners
por: Zhang, Yanan, et al.
Publicado: (2016)

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma
por: Wen, Ying, et al.
Publicado: (2018)

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis
por: Schönenberger, Désirée, et al.
Publicado: (2016)

HIF-1α Overexpression Induces Angiogenesis in Mesenchymal Stem Cells
por: Razban, Vahid, et al.
Publicado: (2012)

HIF-1α Contributes to Proliferation and Invasiveness of Neuroblastoma Cells via SHH Signaling
por: Chen, Sheng, et al.
Publicado: (2015)

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer
por: Wang, Yu-Zhao, et al.
Publicado: (2023)

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis
por: Krzywinska, Ewelina, et al.
Publicado: (2017)

Pluronic(®) L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse hindlimb ischemia
por: Song, Hongmei, et al.
Publicado: (2014)

Targeting Angiogenesis for Controlling Neuroblastoma
por: Roy Choudhury, Subhasree, et al.
Publicado: (2012)

A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling
por: Shao, Jingjing, et al.
Publicado: (2022)

Sunitinib Suppress Neuroblastoma Growth through Degradation of MYCN and Inhibition of Angiogenesis
por: Calero, Raul, et al.
Publicado: (2014)

Insufficient Radiofrequency Ablation Promotes Angiogenesis of Residual Hepatocellular Carcinoma via HIF-1α/VEGFA
por: Kong, Jian, et al.
Publicado: (2012)

DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer
por: Hou, Pingfu, et al.
Publicado: (2019)

miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
por: Ouyang, Liping, et al.
Publicado: (2021)

Taohong Siwu Decoction Promotes Osteo-Angiogenesis in Fractures by Regulating the HIF-1α Signaling Pathway
por: Tang, Zhi, et al.
Publicado: (2022)

HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma
por: Lai, Xiang-Me, et al.
Publicado: (2017)

HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer
por: Mladenova, Dessislava N., et al.
Publicado: (2015)

The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis
por: Oh, Su Young, et al.
Publicado: (2015)

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
por: Kim, Yunho, et al.
Publicado: (2016)

Effects of siRNA-mediated HIF-1α gene silencing on angiogenesis in osteosarcoma
por: Zhang, Xu-dong, et al.
Publicado: (2017)

Succinate at the Crossroad of Metabolism and Angiogenesis: Roles of SDH, HIF1α and SUCNR1
por: Atallah, Reham, et al.
Publicado: (2022)

CD55 is a HIF-2α marker with anti-adhesive and pro-invading properties in neuroblastoma
por: Cimmino, F, et al.
Publicado: (2016)

HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway
por: Song, Shuang, et al.
Publicado: (2023)

PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation
por: Azoitei, Ninel, et al.
Publicado: (2016)

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma
por: Hagenbuchner, Judith, et al.
Publicado: (2016)

EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis
por: Onufer, Emily J., et al.
Publicado: (2020)

Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
por: Zhang, Sheng, et al.
Publicado: (2020)

HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases
por: Chen, Wei, et al.
Publicado: (2022)

Secreted phosphoprotein 1 promotes angiogenesis of glioblastoma through upregulating PSMA expression via transcription factor HIF1α: SPP1 promotes angiogenesis of glioblastoma
por: Tu, Wenjing, et al.
Publicado: (2022)

Quercetin Downregulates Cyclooxygenase-2 Expression and HIF-1α/VEGF Signaling-Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm
por: Wang, Lian, et al.
Publicado: (2020)

Swimming attenuates tumor growth in CT-26 tumor-bearing mice and suppresses angiogenesis by mediating the HIF-1α/VEGFA pathway
por: Li, Jiapeng, et al.
Publicado: (2022)

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
por: Schipani, Ernestina, et al.
Publicado: (2009)

Stabilization of HIF-2α impacts pancreas growth
por: Flores-Martínez, Alvaro, et al.
Publicado: (2018)

α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis
por: Jiang, Tian-Tian, et al.
Publicado: (2021)

Houshiheisan promotes angiogenesis via HIF-1α/VEGF and SDF-1/CXCR4 pathways: in vivo and in vitro
por: Xiang, Yangyang, et al.
Publicado: (2019)

SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species
por: Yang, Zhou, et al.
Publicado: (2021)

tiRNA-Val promotes angiogenesis via Sirt1–Hif-1α axis in mice with diabetic retinopathy
por: Xu, Yan, et al.
Publicado: (2022)

Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer
por: Chen, Yi-Hong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_troh7qtkk1ink03cmavt86l0fg