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Design of Multi-Specificity in Protein Interfaces

Interactions in protein networks may place constraints on protein interface sequences to maintain correct and avoid unwanted interactions. Here we describe a “multi-constraint” protein design protocol to predict sequences optimized for multiple criteria, such as maintaining sets of interactions, and...

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Detalles Bibliográficos
Autores principales: Humphris, Elisabeth L, Kortemme, Tanja
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950952/
https://www.ncbi.nlm.nih.gov/pubmed/17722975
http://dx.doi.org/10.1371/journal.pcbi.0030164