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Design of Multi-Specificity in Protein Interfaces
Interactions in protein networks may place constraints on protein interface sequences to maintain correct and avoid unwanted interactions. Here we describe a “multi-constraint” protein design protocol to predict sequences optimized for multiple criteria, such as maintaining sets of interactions, and...
Autores principales: | Humphris, Elisabeth L, Kortemme, Tanja |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950952/ https://www.ncbi.nlm.nih.gov/pubmed/17722975 http://dx.doi.org/10.1371/journal.pcbi.0030164 |
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