A Discrete Class of Intergenic DNA Dictates Meiotic DNA Break Hotspots in Fission Yeast

Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends. Like recombination events, DSBs occur at hotspots in the genome, but the genetic factors responsible for most hotspots have remained elusive....

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Detalles Bibliográficos
Autores principales: Cromie, Gareth A, Hyppa, Randy W, Cam, Hugh P, Farah, Joseph A, Grewal, Shiv I. S, Smith, Gerald R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950956/
https://www.ncbi.nlm.nih.gov/pubmed/17722984
http://dx.doi.org/10.1371/journal.pgen.0030141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950956/
https://www.ncbi.nlm.nih.gov/pubmed/17722984
http://dx.doi.org/10.1371/journal.pgen.0030141

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