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Linkage Disequilibrium in Wild Mice

Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causative genes have been identified. The main difficulty is the ex...

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Detalles Bibliográficos
Autores principales: Laurie, Cathy C, Nickerson, Deborah A, Anderson, Amy D, Weir, Bruce S, Livingston, Robert J, Dean, Matthew D, Smith, Kimberly L, Schadt, Eric E, Nachman, Michael W
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950958/
https://www.ncbi.nlm.nih.gov/pubmed/17722986
http://dx.doi.org/10.1371/journal.pgen.0030144