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Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins

BACKGROUND: While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well understood. One hypothesis is that similarities between HIV and human protein...

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Detalles Bibliográficos
Autores principales: Rolland, Morgane, Nickle, David C., Deng, Wenjie, Frahm, Nicole, Brander, Christian, Learn, Gerald H., Heckerman, David, Jojic, Nebosja, Jojic, Vladimir, Walker, Bruce D., Mullins, James I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952107/
https://www.ncbi.nlm.nih.gov/pubmed/17786195
http://dx.doi.org/10.1371/journal.pone.0000823