Deletion of the N-terminus of SF2/ASF Permits RS-Domain-Independent Pre-mRNA Splicing

Serine/arginine-rich (SR) proteins are essential splicing factors with one or two RNA-recognition motifs (RRMs) and a C-terminal arginine- and serine-rich (RS) domain. SR proteins bind to exonic splicing enhancers via their RRM(s), and from this position are thought to promote splicing by antagonizi...

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Detalles Bibliográficos
Autores principales: Shaw, Stephanie D., Chakrabarti, Sutapa, Ghosh, Gourisankar, Krainer, Adrian R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952110/
https://www.ncbi.nlm.nih.gov/pubmed/17786225
http://dx.doi.org/10.1371/journal.pone.0000854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952110/
https://www.ncbi.nlm.nih.gov/pubmed/17786225
http://dx.doi.org/10.1371/journal.pone.0000854

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