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Deletion of the N-terminus of SF2/ASF Permits RS-Domain-Independent Pre-mRNA Splicing

Serine/arginine-rich (SR) proteins are essential splicing factors with one or two RNA-recognition motifs (RRMs) and a C-terminal arginine- and serine-rich (RS) domain. SR proteins bind to exonic splicing enhancers via their RRM(s), and from this position are thought to promote splicing by antagonizi...

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Detalles Bibliográficos
Autores principales:	Shaw, Stephanie D., Chakrabarti, Sutapa, Ghosh, Gourisankar, Krainer, Adrian R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952110/ https://www.ncbi.nlm.nih.gov/pubmed/17786225 http://dx.doi.org/10.1371/journal.pone.0000854

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