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Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges

Recombinant proteins are being evaluated as smallpox and monkeypox vaccines because of their perceived safety compared to live vaccinia virus. Previously, we demonstrated that three or more injections of a Ribi-type adjuvant with a combination of three proteins from the outer membranes of intracellu...

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Detalles Bibliográficos
Autores principales: Fogg, Christiana N., Americo, Jeffrey L., Lustig, Shlomo, Huggins, John W., Smith, Scott K., Damon, Inger, Resch, Wolfgang, Earl, Patricia L., Klinman, Dennis M., Moss, Bernard
Formato: Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952660/
https://www.ncbi.nlm.nih.gov/pubmed/17229505
http://dx.doi.org/10.1016/j.vaccine.2006.12.037