Mechanistic role of a disease-associated genetic variant within the ADAM33 asthma susceptibility gene

BACKGROUND: ADAM33 has been identified as an asthma-associated gene in an out-bred population. Genetic studies suggested that the functional role of this metalloprotease was in airway remodeling. However, the mechanistic roles of the disease-associated SNPs have yet to be elucidated especially in th...

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Detalles Bibliográficos
Autores principales: Del Mastro, Richard G, Turenne, Laura, Giese, Heidi, Keith, Tim P, Van Eerdewegh, Paul, May, Klaus JW, Little, Randall D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955437/
https://www.ncbi.nlm.nih.gov/pubmed/17640346
http://dx.doi.org/10.1186/1471-2350-8-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955437/
https://www.ncbi.nlm.nih.gov/pubmed/17640346
http://dx.doi.org/10.1186/1471-2350-8-46

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