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Mechanistic role of a disease-associated genetic variant within the ADAM33 asthma susceptibility gene
BACKGROUND: ADAM33 has been identified as an asthma-associated gene in an out-bred population. Genetic studies suggested that the functional role of this metalloprotease was in airway remodeling. However, the mechanistic roles of the disease-associated SNPs have yet to be elucidated especially in th...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955437/ https://www.ncbi.nlm.nih.gov/pubmed/17640346 http://dx.doi.org/10.1186/1471-2350-8-46 |