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An exfoliation and enrichment strategy results in improved transcriptional profiles when compared to matched formalin fixed samples

BACKGROUND: Identifying the influence formalin fixation has on RNA integrity and recovery from clinical tissue specimens is integral to determining the utility of using archival tissue blocks in future molecular studies. For clinical material, the current gold standard is unfixed tissue that has bee...

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Detalles Bibliográficos
Autores principales: Mojica, Wilfrido D, Stein, Leighton, Hawthorn, Lesleyann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955442/
https://www.ncbi.nlm.nih.gov/pubmed/17683544
http://dx.doi.org/10.1186/1472-6890-7-7