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A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance

BACKGROUND: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently, it has been reported in the literature that the FDR is not well controlled by SAM. Due to the vast application of SAM i...

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Detalles Bibliográficos
Autor principal: Zhang, Shunpu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955751/
https://www.ncbi.nlm.nih.gov/pubmed/17603887
http://dx.doi.org/10.1186/1471-2105-8-230