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Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus – 1 (HIV-1) infected pediatric patients: a cross-sectional study

BACKGROUND: Although the introduction of combined therapy with reverse transcriptase and protease inhibitors has resulted in considerable decrease in HIV related mortality; it has also induced the development of multiple drug-resistant HIV-1 variants. The few studies on HIV-1 mutagenesis in HIV infe...

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Detalles Bibliográficos
Autores principales: Malhotra, Amisha, Gaur, Sunanda, Whitley-Williams, Patricia, Loomis, Caitlin, Petrova, Anna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959238/
https://www.ncbi.nlm.nih.gov/pubmed/17620130
http://dx.doi.org/10.1186/1742-6405-4-15