Cargando…
Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus – 1 (HIV-1) infected pediatric patients: a cross-sectional study
BACKGROUND: Although the introduction of combined therapy with reverse transcriptase and protease inhibitors has resulted in considerable decrease in HIV related mortality; it has also induced the development of multiple drug-resistant HIV-1 variants. The few studies on HIV-1 mutagenesis in HIV infe...
Autores principales: | Malhotra, Amisha, Gaur, Sunanda, Whitley-Williams, Patricia, Loomis, Caitlin, Petrova, Anna |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959238/ https://www.ncbi.nlm.nih.gov/pubmed/17620130 http://dx.doi.org/10.1186/1742-6405-4-15 |
Ejemplares similares
-
Mutations in the Reverse Transcriptase and Protease Genes of Human Immunodeficiency Virus-1 from Antiretroviral Naïve and Treated Pediatric Patients
por: Bure, Dinesh, et al.
Publicado: (2015) -
Epistasis as a Determinant of the HIV-1 Protease's Robustness to Mutation
por: Capel, Elena, et al.
Publicado: (2014) -
Kiwifruit protease Act d 1 compromises the intestinal barrier by disrupting tight junctions
por: Grozdanovic, Milica, et al.
Publicado: (2014) -
Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance
por: Babrzadeh, Farbod, et al.
Publicado: (2013) -
Analysis of correlated mutations in HIV-1 protease using spectral clustering
por: Liu, Ying, et al.
Publicado: (2008)