Synthesis of two potential NK(1)-receptor ligands using [1-(11)C]ethyl iodide and [1-(11)C]propyl iodide and initial PET-imaging

BACKGROUND: The previously validated NK(1)-receptor ligand [O-methyl-(11)C]GR205171 binds with a high affinity to the NK(1)-receptor and displays a slow dissociation from the receptor. Hence, it cannot be used in vivo for detecting concentration changes in substance P, the endogenous ligand for the...

Descripción completa

Detalles Bibliográficos
Autores principales: Syvänen, Stina, Eriksson, Jonas, Genchel, Tove, Lindhe, Örjan, Antoni, Gunnar, Långström, Bengt
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959516/
https://www.ncbi.nlm.nih.gov/pubmed/17663770
http://dx.doi.org/10.1186/1471-2342-7-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959516/
https://www.ncbi.nlm.nih.gov/pubmed/17663770
http://dx.doi.org/10.1186/1471-2342-7-6

Ejemplares similares