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Genome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways

BACKGROUND: Human natural killer (NK) cells are the key contributors of innate immune response and the effector functions of these cells are enhanced by cytokines such as interleukine 2 (IL2). We utilized genome-wide transcriptional profiling to identify gene expression signatures and pathways in re...

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Detalles Bibliográficos
Autores principales: Dybkaer, Karen, Iqbal, Javeed, Zhou, Guimei, Geng, Huimin, Xiao, Li, Schmitz, Alexander, d'Amore, Francesco, Chan, Wing C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959522/
https://www.ncbi.nlm.nih.gov/pubmed/17623099
http://dx.doi.org/10.1186/1471-2164-8-230