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An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length

In the nucleus of eukaryotic cells, histone proteins organize the linear genome into a functional and hierarchical architecture. In this paper, we use the crystal structures of the nucleosome core particle, B-DNA and the globular domain of H5 linker histone to build the first all-atom model of compa...

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Detalles Bibliográficos
Autores principales: Wong, Hua, Victor, Jean-Marc, Mozziconacci, Julien
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963316/
https://www.ncbi.nlm.nih.gov/pubmed/17849006
http://dx.doi.org/10.1371/journal.pone.0000877