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PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer

BACKGROUND: The sodium/iodide symporter (NIS) is a membrane glycoprotein mediating active iodide uptake in the thyroid gland and is the molecular basis for radioiodide imaging and therapeutic ablation of thyroid carcinomas. NIS is expressed in the lactating mammary gland and in many human breast tum...

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Detalles Bibliográficos
Autores principales: Knostman, Katherine AB, McCubrey, James A, Morrison, Carl D, Zhang, Zhaoxia, Capen, Charles C, Jhiang, Sissy M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963336/
https://www.ncbi.nlm.nih.gov/pubmed/17651485
http://dx.doi.org/10.1186/1471-2407-7-137