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Pathway Switching Explains the Sharp Response Characteristic of Hypoxia Response Network
Hypoxia induces the expression of genes that alter metabolism through the hypoxia-inducible factor (HIF). A theoretical model based on differential equations of the hypoxia response network has been previously proposed in which a sharp response to changes in oxygen concentration was observed but not...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963493/ https://www.ncbi.nlm.nih.gov/pubmed/17784783 http://dx.doi.org/10.1371/journal.pcbi.0030171 |