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Intraepithelial and Interstitial Deposition of Pathological Prion Protein in Kidneys of Scrapie-Affected Sheep

Prions have been documented in extra-neuronal and extra-lymphatic tissues of humans and various ruminants affected by Transmissible Spongiform Encephalopathy (TSE). The presence of prion infectivity detected in cervid and ovine blood tempted us to reason that kidney, the organ filtrating blood deriv...

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Detalles Bibliográficos
Autores principales: Ligios, Ciriaco, Cancedda, Giovanna Maria, Margalith, Ilan, Santucciu, Cinzia, Madau, Laura, Maestrale, Caterina, Basagni, Massimo, Saba, Mariangela, Heikenwalder, Mathias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964536/
https://www.ncbi.nlm.nih.gov/pubmed/17848990
http://dx.doi.org/10.1371/journal.pone.0000859