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DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets

BACKGROUND: The epigenetics of ovarian carcinogenesis remains poorly described. We have in the present study investigated the promoter methylation status of 13 genes in primary ovarian carcinomas (n = 52) and their in vitro models (n = 4; ES-2, OV-90, OVCAR-3, and SKOV-3) by methylation-specific pol...

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Detalles Bibliográficos
Autores principales: Wu, Qinghua, Lothe, Ragnhild A, Ahlquist, Terje, Silins, Ilvars, Tropé, Claes G, Micci, Francesca, Nesland, Jahn M, Suo, Zhenhe, Lind, Guro E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964763/
https://www.ncbi.nlm.nih.gov/pubmed/17623056
http://dx.doi.org/10.1186/1476-4598-6-45