Cargando…

Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation

BACKGROUND: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main ORF by interfering with translational reinitiation at the main start codon. uORFs also occur by chance in the genome, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Cvijović, Marija, Dalevi, Daniel, Bilsland, Elizabeth, Kemp, Graham JL, Sunnerhagen, Per
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964767/
https://www.ncbi.nlm.nih.gov/pubmed/17686169
http://dx.doi.org/10.1186/1471-2105-8-295