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Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
BACKGROUND: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main ORF by interfering with translational reinitiation at the main start codon. uORFs also occur by chance in the genome, in...
Autores principales: | Cvijović, Marija, Dalevi, Daniel, Bilsland, Elizabeth, Kemp, Graham JL, Sunnerhagen, Per |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964767/ https://www.ncbi.nlm.nih.gov/pubmed/17686169 http://dx.doi.org/10.1186/1471-2105-8-295 |
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