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Deletion of Ultraconserved Elements Yields Viable Mice
Ultraconserved elements have been suggested to retain extended perfect sequence identity between the human, mouse, and rat genomes due to essential functional properties. To investigate the necessities of these elements in vivo, we removed four noncoding ultraconserved elements (ranging in length fr...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964772/ https://www.ncbi.nlm.nih.gov/pubmed/17803355 http://dx.doi.org/10.1371/journal.pbio.0050234 |