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Heritable Stochastic Switching Revealed by Single-Cell Genealogy

The partitioning and subsequent inheritance of cellular factors like proteins and RNAs is a ubiquitous feature of cell division. However, direct quantitative measures of how such nongenetic inheritance affects subsequent changes in gene expression have been lacking. We tracked families of the yeast...

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Detalles Bibliográficos
Autores principales: Kaufmann, Benjamin B, Yang, Qiong, Mettetal, Jerome T, van Oudenaarden, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964776/
https://www.ncbi.nlm.nih.gov/pubmed/17803359
http://dx.doi.org/10.1371/journal.pbio.0050239