Molecular and Structural Discrimination of Proline Racemase and Hydroxyproline-2-Epimerase from Nosocomial and Bacterial Pathogens

The first eukaryotic proline racemase (PRAC), isolated from the human Trypanosoma cruzi pathogen, is a validated therapeutic target against Chagas' disease. This essential enzyme is implicated in parasite life cycle and infectivity and its ability to trigger host B-cell nonspecific hypergammagl...

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Detalles Bibliográficos
Autores principales: Goytia, Maira, Chamond, Nathalie, Cosson, Alain, Coatnoan, Nicolas, Hermant, Daniel, Berneman, Armand, Minoprio, Paola
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964878/
https://www.ncbi.nlm.nih.gov/pubmed/17849014
http://dx.doi.org/10.1371/journal.pone.0000885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964878/
https://www.ncbi.nlm.nih.gov/pubmed/17849014
http://dx.doi.org/10.1371/journal.pone.0000885

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