Lead Induces Chondrogenesis and Alters Transforming Growth Factor-β and Bone Morphogenetic Protein Signaling in Mesenchymal Cell Populations

BACKGROUND: It has been established that skeletal growth is stunted in lead-exposed children. Because chondrogenesis is a seminal step during skeletal development, elucidating the impact of Pb on this process is the first step toward understanding the mechanism of Pb toxicity in the skeleton. OBJECT...

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Detalles Bibliográficos
Autores principales: Zuscik, Michael J., Ma, Lin, Buckley, Taylor, Puzas, J. Edward, Drissi, Hicham, Schwarz, Edward M., O’Keefe, Regis J.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964910/
https://www.ncbi.nlm.nih.gov/pubmed/17805416
http://dx.doi.org/10.1289/ehp.10028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964910/
https://www.ncbi.nlm.nih.gov/pubmed/17805416
http://dx.doi.org/10.1289/ehp.10028

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