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Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth

BACKGROUND: Angiogenesis is a fundamental process that allows tumor growth by providing nutrients and oxygen to the tumor cells. Beyond the oxygen diffusion limit from a capillary blood vessel, tumor cells become apoptotic. Angiogenesis results from a balance of pro- and anti-angiogenic stimuli. End...

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Detalles Bibliográficos
Autores principales: Paschoalin, Thaysa, Carmona, Adriana K, Rodrigues, Elaine G, Oliveira, Vitor, Monteiro, Hugo P, Juliano, Maria A, Juliano, Luiz, Travassos, Luiz R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1965469/
https://www.ncbi.nlm.nih.gov/pubmed/17620116
http://dx.doi.org/10.1186/1476-4598-6-44