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Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans.

Estraumustine phosphate (EMP), a cytotoxic drug used in the treatment of prostatic carcinoma, has been shown to exert cytotoxic effects on glioma cells in vitro. The drug uptake is assumed to depend on a specific estramustine binding protein (EMBP). One of the main difficulties in achieving cytotoxi...

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Detalles Bibliográficos
Autores principales: Bergenheim, A. T., Gunnarsson, P. O., Edman, K., von Schoultz, E., Hariz, M. I., Henriksson, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968176/
https://www.ncbi.nlm.nih.gov/pubmed/8431366