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Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.

Murine L5178Y-ML cells, when transplanted subcutaneously into the flank of (BALB/c x DBA/2)F1 mice, grew locally and always formed spontaneous metastases in the liver. Even after surgical removal of the primary tumour mass 5 or 7 days after tumour cell inoculation, all mice died due to liver metasta...

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Detalles Bibliográficos
Autores principales: Sugihara, S., Yamamoto, T., Tanaka, H., Kambara, T., Hiraoka, T., Miyauchi, Y.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968215/
https://www.ncbi.nlm.nih.gov/pubmed/8427781